I saw elsewhere - perhaps Twitter - a criticism of the #cyberpunk idea, reflected in Cyberpunk 2077, that the unaltered human body is somehow sacred, and that augmenting it is profane. The criticism noted that this was, at its core, transphobic.

The critic then turned the idea on its head into a trans-positive cyberpunk that eschewed "humanity" in favor of "essence". Maybe one person's essence is complete when they're born; maybe another's essence is lacking until they augment themselves.