@photex In a realtime context or an audio production/recording context? For the latter I have a bunch of quick shortcuts to achieving crushing adequacy which I should probably write up someday.
@photex for both things a good starting point is to give everything its own little place in the audio spectrum. Notch EQ is the most powerful mixing tip that I can share.
@photex sidechain compression is also good to have, although that's less prevalent in realtime engines.