At least 3 times Dune got reinterpreted;
* George Lucas saw a desert where harvesting water was all important and went, hey this is basically Modesto.
* Games Workshop designers saw elite soldiers putting spiritual faith in their Emperor and weird mutant navigators in a place where it rains constantly.
* Alejandro Jodorowski went “space emperors, nuns and warrior codes are cool, but this is kind of bland and there’s not enough sex or blood.”