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Dune, gross bodily functions, the Gom Jabbar 

"Bladder... full. It's been hours since you last went. Your kidneys aching. Barely able to hold it. Water sloshing... Sloshing... Sloshing."
"GOTTA PEEEEEEE."
"Kul wahlad! No woman child ever took that much! You may go to the bathroom, young human."
* Paul races down the hall at top speeds, tensing PC muscles the whole time *

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