loneliness
Technically a subtoot, but it's really subtooting myself.
You can adapt to feelings of loneliness. Even rejection and abandonment and loneliness. A cast of OCs who're crazy about you help, although that way lies a particular rabbit hole that can close up behind you if you dig too deep. OTOH, all perception happens inside your head anyhow, so who's to say a feeling of belonging and family and friendship that's entirely fictional is different from one forged in the Meatworld?
loneliness
@Phorm *chuckles, amidst hugs* Oh, I *am* adapted, djear djinna: after half a decade of being out of my mind in psychotic denial, I've embraced it. I accept it's the background radiation static all my thoughts rise out of: I could be in amazing relationships with constant people everywhere all the time and I'd *still* struggle with loneliness. It was compiled in during the build process, inextricable.
Like the poster says, 'pain is inevitable: suffering may be optional'.
loneliness
@Momentrabbit For whatever it's worth: Me, too.