A culinary challenge that just came to mind: Find a good way to combine Asian-style noodle dishes with Italian-style pasta dishes, in a way that feels only minimally forced and doesn't taste weird.
@JulieSqveakaroo I think you could make most types of noodle work well with most types of sauce; the challenge is to get something that makes one wonder whether it's Italian or Asian.
Mixing soy sauce with marinara, for example, though I doubt that would taste too good on its own.
@Rosemary
Vermicelli pairs very well with stir fry and thai sauces.