I wonder how, if it ever would, how Persona would handle non-human identity in its setting.
Persona has had a bunch of explicitly non-human Persona users - ie. jungian shadows, a dog, a few robots - but non-humanness as an identity could be interesting in its universe exploring the myths given life from the collective unconscious.
But still, it's because Persona is more interested in exploring how people interact and their goals and roles in life, that I suspect identity as a personal meaning and "self-definition" isn't actually something it's likely to focus on. If one could create a story about the "function" behind being non-human, as a role in human society, then that's something it could possibly explore.
... to be fair, maybe all the Persona-users are non-human and species-fluid anyway. "I am thou, thou art I", after all.