This is funnier without context.

However, I do prefer to cite sources and context when I can, so:

Pictured on the left: Otto Octavius, in his civilian guise of Professor Elliot Tolliver. His body is a clone of Peter Parker with some Otto DNA thrown in, his mind is the same Otto who transferred into Peter's head to escape death, became the Superior Spider-Man for a time, and for a while was stuck in the body of the Living Brain robot (green thing in back left).

In this panel: Anna Maria, a genius who fell for Otto when he was Peter but later broke up with him when the deception was broken, has recognized Otto in his new body and confronted him, about to arrest him because he's a villain (except he's not, he's trying to be Spider-Man again). Except in the middle of their discussion, the news comes on with some emergency monster attacking the city. Otto makes this face at Anna to say 'going to let me go handle that'?

This is from Superior Spider-Man #1 (a new series), by Christos Gage and Mike Hawthorne.

See? Told you it was funnier without. :-P