@Felthry According to the Nintendo website, original Gameboy games aren't always compatible with newer consoles:
A very small number of older games may not function properly on the Game Boy Color, Game Boy Advance, or Game Boy Advance SP. Common symptoms include scrambled images, missing graphics, or sound problems.
https://www.nintendo.com/consumer/systems/gameboy/compatibilitychart.jsp
In general I'd guess compatibility is pretty high since it's mostly hardware